Sergio M Borghi Selected Research

kaurenoic acid

1/2022	Sphagneticola trilobata (L.) Pruski-derived kaurenoic acid prevents ovalbumin-induced asthma in mice: Effect on Th2 cytokines, STAT6/GATA-3 signaling, NFκB/Nrf2 redox sensitive pathways, and regulatory T cell phenotype markers.
6/2021	The diterpene from Sphagneticola trilobata (L.) Pruski, kaurenoic acid, reduces lipopolysaccharide-induced peritonitis and pain in mice.

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Sergio M Borghi Research Topics

Disease

28	Pain (Aches) 12/2022 - 06/2013
27	Hyperalgesia 12/2022 - 06/2013
16	Inflammation (Inflammations) 06/2021 - 02/2015
11	Edema (Dropsy) 01/2021 - 01/2017
7	Arthritis (Polyarthritis) 12/2019 - 01/2018
6	Gout 01/2022 - 01/2018
3	Peritonitis 01/2022 - 01/2020
3	Chronic Pain 07/2021 - 02/2015
3	Infections 06/2021 - 04/2017
3	Myalgia 01/2016 - 04/2014
2	Gouty Arthritis 01/2022 - 01/2018
2	Necrosis 03/2019 - 04/2015
2	Hypersensitivity (Allergy) 01/2019 - 01/2018
2	Proteinuria 09/2018 - 06/2017
2	Acute Kidney Injury (Acute Renal Failure) 09/2018 - 06/2017
1	Asthma (Bronchial Asthma) 01/2022
1	COVID-19 01/2022
1	Scorpion Stings 09/2021
1	Ulcerative Colitis 01/2021
1	Colitis 01/2021
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021
1	Chagas Disease (American Trypanosomiasis) 01/2020
1	Parasitemia 01/2020
1	Myelitis 08/2019
1	Neuroinflammatory Diseases 01/2019

Drug/Important Bio-Agent (IBA)

23	CytokinesIBA 12/2022 - 06/2013
12	Analgesics (Analgesic Drugs)IBA 01/2022 - 06/2013
7	FlavonoidsIBA 01/2021 - 02/2015
6	Peroxidase (Myeloperoxidase)IBA 09/2021 - 07/2014
6	Etanercept (Enbrel)FDA Link 09/2021 - 04/2014
6	Superoxides (Superoxide)IBA 06/2021 - 12/2015
5	CarrageenanIBA 12/2022 - 06/2013
5	Uric Acid (Urate)IBA 01/2022 - 01/2018
5	prolinedithiocarbamate (PDTC)IBA 09/2021 - 06/2016
4	Freund's AdjuvantIBA 12/2022 - 06/2013
4	LipidsIBA 01/2022 - 01/2019
4	Interleukin-10 (Interleukin 10)IBA 01/2022 - 02/2015
4	LipopolysaccharidesIBA 01/2022 - 01/2016
4	AntioxidantsIBA 07/2021 - 12/2015
4	InflammasomesIBA 12/2019 - 01/2018
4	Messenger RNA (mRNA)IBA 05/2019 - 01/2017
3	phenylbenzoquinoneIBA 12/2022 - 06/2013
3	Formaldehyde (Formol)FDA Link 12/2022 - 06/2013
3	Capsaicin (Zostrix)FDA Link 01/2022 - 06/2013
3	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 09/2021 - 02/2015
3	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 09/2021 - 07/2014
3	pyrrolidine dithiocarbamic acidIBA 09/2021 - 06/2016
3	Chalcone (Benzalacetophenone)IBA 01/2021 - 02/2015
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 02/2015
3	QuercetinIBA 12/2019 - 01/2016
3	Type I Tumor Necrosis Factor ReceptorsIBA 04/2017 - 04/2014
2	kaurenoic acidIBA 01/2022 - 06/2021
2	ZymosanIBA 01/2022 - 12/2019
2	2,2'- azino- di- (3- ethylbenzothiazoline)- 6- sulfonic acid (ABTS)IBA 06/2021 - 06/2018
2	HesperidinIBA 01/2021 - 02/2015
2	Acetic Acid (Vinegar)FDA LinkGeneric 01/2021 - 02/2015
2	ChemokinesIBA 01/2020 - 05/2019
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 12/2019 - 02/2015
2	naringeninIBA 12/2019 - 01/2016
2	Type II Tumor Necrosis Factor ReceptorsIBA 05/2019 - 04/2017
2	vinpocetineIBA 01/2019 - 06/2017
2	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 01/2019 - 09/2018
2	7,14- dihydroxydocosa- 4,8,10,12,16,19- hexaenoic acidIBA 01/2019 - 01/2019
2	Diclofenac (SR 38)FDA LinkGeneric 09/2018 - 06/2017
2	Urea (Carbamide)FDA LinkGeneric 09/2018 - 06/2017
2	CreatinineIBA 09/2018 - 06/2017
2	salicylhydroxamic acid (SHAM)IBA 04/2015 - 07/2014
2	InterleukinsIBA 02/2015 - 07/2014
2	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 02/2015 - 04/2014
1	OvalbuminIBA 01/2022
1	AntigensIBA 01/2022
1	2,3,4-tri-O-acetylarabinopyranosyl isothiocyanate (AITC)IBA 01/2022
1	LeptinIBA 01/2022
1	NF-kappa B (NF-kB)IBA 09/2021
1	VenomsIBA 09/2021
1	Acetylglucosaminidase (NAGase)IBA 09/2021
1	DiterpenesIBA 06/2021
1	Thiobarbituric Acid Reactive SubstancesIBA 06/2021
1	Minocycline (Cyclops)FDA LinkGeneric 05/2021
1	Metalloproteases (Metalloproteinases)IBA 05/2021
1	Bothrops jararaca VenomIBA 05/2021
1	Snake Venoms (Snake Venom)IBA 05/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2021
1	Interleukin-33IBA 01/2021
1	Diosmin (Daflon)IBA 01/2020
1	Rutin (Rutoside)IBA 12/2019
1	flavanoneIBA 12/2019
1	3-hydroxyflavoneIBA 12/2019
1	Probucol (Lorelco)FDA Link 08/2019
1	Neutralizing AntibodiesIBA 05/2019
1	Acetaminophen (Paracetamol)FDA LinkGeneric 03/2019
1	Docosahexaenoic AcidsIBA 01/2019
1	CollagenIBA 01/2019
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019
1	Adenosine Triphosphate (ATP)IBA 01/2019
1	potassium superoxideIBA 01/2019
1	bis(bipyridyl)ruthenium(II)IBA 01/2019

Therapy/Procedure

4	Therapeutics 01/2022 - 02/2015
2	Traditional Medicine (Folk Remedies) 01/2022 - 06/2021
2	Analgesia 07/2021 - 12/2019